Distributed Folding, Проект занимается моделированием белков Налаштування

[nikelong]

Проект "Distributed Folding"

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• Официальный сайт
• Статистика по команде "Ukraine"

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ТОП-20 участников:

Distributed Folding Project Statistics
as of: Tue Oct  5 12:09:59 2004 EST

Ukraine Team Page (Rank: 341)
(* = team leader)

Total team structures:     1,625,822

Team Statistics
Rank             UID            Username                 Organization    # points (current protein)             # points (total)    Best RMS in A
#1.           25208              lesnik                  Lesnik Team                            0                    1,164,047    99.999
#2.           32989               Death                     Business                      251,714                      251,714    9.480
#3.           25989              rostik                         home                            0                      133,743    99.999
#4.           26896           marchelly                        MacOS                            0                       45,531    99.999
#5.           25366             Karlson                                                         0                       30,787    99.999

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Дата основания команды - 2003 Капитан - Deth
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Наши пять участников привели команду к финишу на 341-м месте.
Лучший из наших, Лесник, занял 3054-е место в мире.

О проекте:
Проект приостановлен с октября-2004.

Проект занимается моделированием белков с помощью какого-то нового хитрого алгоритма. В ходе проекта планируют проверить его надёжность и получить данные, важные для понимания причин многих болезней. В будущем это поможет для ускорения создавания лекарств.

Авторы плодовиты на количество версий клиента: доступны для загрузки клиенты для 16-ти платформ (даже для sony playstation 2 есть! о_0).

Проект приостановлен с октября 2004 года.

Результаты:

Results
Results for Phase Ia
As Phase Ia of the project has been completed, results for the first five small proteins are now available, along with the corresponding statistics and analysis. The proteins are presented in the order that they were worked on. Please select one of the 5 proteins listed on the left for detailed result information.

Notes:

1. For all proteins, the native protein is represented in yellow, whereas the best protein generated by one of the members is represented in blue.
2. All results for part I are screenshots and there are no links.


* 1ENH
* 1PMC
* 5PTI
* 1VII
* 1SHG

Results from the CASP5 Experiment
Here you can find the completed and submitted results for the CASP5 Experiment, based on the results we collected from Distributed Folding. Users folded each protein for the duration of 1 week, generating roughly 1 billion structures, and each protein submission consists of the top 5 structures. Structures were ranked both by pseudo-energy (computed by the folding clients throughout the experiment) and other more time-consuming scoring functions. The best structure generated by each individual user was scored with a battery of scoring functions and the final top 5 chosen from this detailed analysis. Only the top structure is presented for each protein. The others may be viewed with Cn3D.

* T0129
* T0131
* T0135
* T0138
* T0139
* T0147n
* T0148
* T0156
* T0157
* T0161
* T0170
* T0180
* T0181

Project Info

* Year of conclusion: 2004
* Number of teams: 693
* Number of participants: 32,132
* Running platforms: Windows, Linux, MacOS X, FreeBSD, Solaris, IRIX, HP-UX, QNX, BeOS

The Distributed Folding project simulated folding proteins to help scientists learn how proteins "fold and assemble into living cells." The project, run by the Samuel Lunenfeld Research Institute, the Hogue Bioinformatics Laboratory and the University of Toronto Department of Biochemistry, and supported by Intel's Philanthropic Peer-to-Peer Program, tested a protein folding algorithm to see if it could reproduce natural protein folds. The project hoped to create "the largest samples of protein folds ever computed." In its first phase, 1a, it made 1 billion folds for five small proteins. In phase 1b it made 10 billion folds for 10 large proteins. Phase 2 began on June 17, 2003 and ended on October 5, 2004. The project received a patent (U.S. Patent number 6490532) for its structure generation algorithm on December 3, 2002. See the results of the proteins which were completed for the project.
Between May 30, 2002 and September 9, 2002, the project competed in the CASP5 structure prediction contest. Results of the competition were made available in late December, 2002. Between July 6, 2004 and August 31, 2004, the project competed in the CASP6 structure prediction contest. Results of the competition were made available on December 24, 2004.

After the project ended, the project team planned to analyze the results of the proteins it had folded with the current algorithm and to create a better folding algorithm for a possible future distributed computing project.

View a Windows Media Player ASF-format file of a television interview by CityPulse24 of the project coordinators on November 27, 2002.

The project software client ran as a screensaver on Win32 and as a text client on Win32, Linux, Sony PlayStation 2 Linux (it was the first distributed computing client to run on this platform), and many Unix platforms including Mac OS X. The project server and client software was also the first to use a ticketing system for submitting results: when the project server was too busy to receive all of the results clients attempted to submit to it, it would assign each client a numbered "ticket," the clients stored their results locally, and then each client could submit its results when the project server "called its ticket."

See a discussion forum about this project.

Количество участников - 32,976

Це повідомлення відредагував nikelong: Aug 29 2010, 23:41